Most of the gut problems that we face are often associated with allergies due to poor and incomplete digestion of foods. This eventually leads to various complications that can worsen in the health condition of the IBD patients, and slow down the processes and chances to achieve and maintain Deep Remission. A main causative factor that can result in numerous sorts of gastrointestinal irritations, allergies are key disease-aggravating indications that IBD patients often deal with. Dairy allergy or lactose intolerance is one among the commonly found allergies that most of the IBD patients keep facing each day. Sufferers of this autoimmune disease are intolerant of several grains. Yeast is yet another allergen that causes gut irritations and related symptoms that can worsen the health of IBD patients. Hence, experts continue to recommend the strong need to adhere to the good ‘stone age diet’ with low glycaemic index. It helps avoid all the allergens that can cause irritations. IBD and related allergic conditions can lead to sudden flare-ups of both inflammation and debilitating symptoms. Hence inflammatory bowel disease patients are advised to avoid certain foods even if they can be categorised as healthy and highly nutritious.

Researches undertaken to unveil the possible link between diet and IBD has analyse a wide range of foods and nutrients, in order to analyse their roles on the gastrointestinal tract. This has helped find the link between IBD and diets, especially the ones that are rich in fats and sugars, as they might soon aggravate the disease symptoms and lead to life threatening flare-ups. Chances of flare-ups are significantly higher among those who choose to have a higher amount of junk foods and westernised diet plans which are high in fats and sugars. Several elements like dairy products and linoleic acid that are considered as inevitable parts of daily diets are symptom-triggering factors that inflammatory bowel disease patients have to avoid by all means.

Although the term deep remission has always been a matter of dispute, especially in cases of patients who suffer from autoimmune disease like ulcerative colitis and Crohn’s disease, it is scientifically defined a disease-free phase, though it varies with the complicated nature of diseases, apart from analysing the different factors that are inevitable to achieving the state of remission, which is essential to regaining and maintaining health and wellness, in situations where a complete cure from the disease condition cannot be made possible. Hence, it is crucial to measuring an analysing the factors that are essential to attaining remission, and maintain the phase for a long time. Inflammatory bowel conditions of all sorts can be chronic and debilitating. Hence accumulation of diagnostic evidences have to be looked upon beyond the clinical symptoms alone, as the disease condition might trigger several non-specific symptoms that can easily complicate the process of diagnosis and thereby adding in more hassles to choosing the therapeutic strategies that are essential to curbing the disease conditions in the quickest possible manner. The entire set of therapeutic goals that are available to curb IBD have been devised with the aim of helping patients achieve deep remission (clinical remission), which is the only way to alter the disease condition that inflammatory bowel disease patients face each day.

While a Crohn’s Disease Activity Index <150 and complete MH might indicate deep remission in Crohn’s disease, the same doesn’t apply to identifying remission in ulcerative colitis, due to lack of a scientific definition for deep remission. When scientifically defined, remission can be classified into several categories:

  1. Clinical remission leads to achieving a symptom-free phase
  2. Biochemical remission is achieved when blood and stool tests that include CRP, ESR, and fecal calprotectin are absolutely normal.
  3. Endoscopic remission can be achieved through mucosal healing through colonoscopy.
  4. Deep (stable) remission is the combination of the aforesaid remissions, defined as achieving a CDAI score < 150 AND, along with complete mucosal healing

 

Each medical treatment for IBD is developed with the aim of helping patients achieve deep remission or symptom-free phase to regain health and wellness, along with maintain remission for the longest timespan without intermittent flare-ups of debilitating symptoms that can quickly deteriorate the health condition of the patients. In order to quickly and effectively accomplish this goal, IBD treatments have to be designed and administered with step-by-step scientific methods that help control intestinal inflammation, a key symptom that worsens IBD conditions. To effectuate this without affecting the rest of bodily functions and the activities of associated organs, a new class of TNF antagonist drugs has been discovered, as it delivers targeted action, and promise improved results and fewer side effects. The reasons that skyrocket the fame and demand of biologics drugs for IBD cure are many, the reason the following FDA approved drugs are recommended by physicians from all over the world:

  1. Cimzia (certolizumab)

  2. Humira (adalimumab)

  3. Remicade (infliximab)

  4. Tysabri (natalizumab)

Biologics medications are developed from living organisms and their various products like proteins. They help supress the inflammatory response in IBD patients by targeting the disease causing molecules like cytokines that are actively involved in the process of triggering acute inflammations. They deliver guaranteed result by inhibiting the illness causing actions of tumour necrosis factor, interleukins, adhesion molecules, colony-stimulating factors, and several other agents. Comprehensive learning of the functioning of these inflammation-causing factors have helped researchers develop and recommend personalized treatments that cure IBD inflammations of all stages. While corticosteroids and several other IBD therapy drugs work on supressing the immune system as a whole, biologics offer an advantage that promises selective action through the targeting of defective and deficient enzymes. Researchers around the world are keen on developing more biologic therapies that help ease biologic treatments for IBD cure.

More information can be obtained on https://www.gutpeople.net a bespoke social networking website, developed solely for gastroenterologists around the world. GI health care experts who specialize in GI disorders can register with The Gut People and start interacting with top GI experts around the world, on various commonly found gastrointestinal disorders like inflammatory bowel disease and intestinal tuberculosis. The Gut People is also equipped with unique functionalities that help download informative documents on gastrointestinal disorders, as well as their comprehensive diagnosis steps and advance treatment methods.

For more info:   https://www.gutpeople.net